The occurrence of marker cells in fetal hematopoiesis of beige (Chédiak-Higashi) mouse.
نویسندگان
چکیده
The presence of neutrophils and their precursors with peroxidase-positive and sudanophilic giant granules, which are characteristic of Chédiak-Higashi syndrome (CHS), in the fetal liver and blood of beige (CH), but not of the control C 57 Black, mice was observed. This finding supports the view that the prenatal diagnosis could be possible, if the fetal blood specimen is obtainable safely, assuming the occurrence of similar marker cells in fetal hematopoiesis in CHS of human.
منابع مشابه
Complementation of the beige mutation in cultured cells by episomally replicating murine yeast artificial chromosomes.
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عنوان ژورنال:
- The Tohoku journal of experimental medicine
دوره 140 3 شماره
صفحات -
تاریخ انتشار 1983